My Library

LEADER 00000nam a2200289 a 4500 
001    u24466 
001    25081 
003    SIRSI 
005    20080106172300.0 
008    060108s1996    flua00000b0000001100eng0d 
020    0849376823 (alk. paper) 
049    JURF 
050 00 RM301.25|bJ33 1996 
100 1  Jackson, Robert C 
245 10 Computer techniques in preclinical and clinical drug 
       development /|cRobert C. Jackson. 
246 30 Preclinical and clinical drug development 
260    Boca Raton :|bCRC Press,|c1996 
300    238 p. :|bill. ;|c24 cm. 
504    Includes bibliographical references (p. 209-220) and 
       index. 
505 0  Introduction: the preclinical and clinical drug 
       development process -- Physiological pharmacokinetic 
       modeling -- Interspecies scaling -- Prediction of drug 
       metabolism and toxicity -- Pharmacodynamic modeling -- 
       Cytokinetic modeling -- Prediction of drug resistance -- 
       Conclusions: the virtual clinical trial -- Appendix: 
       computational pharmacology software suppliers. 
650  0 Drugs|xResearch|xData processing 
650  0 Drugs|xDesign|xComputer simulation