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LEADER 00000cam a2200277 a 4500
001 u45693
003 SIRSI
008 180607s2016 xxua b 001 0 eng d
020 9781785230776
050 04 RM300|b.M35 2016
100 1 McGavock, Hugh
245 10 How drugs work :|bbasic pharmacology for healthcare
professionals /|cHugh McGavock.
250 4th ed
260 Boca Raton, FL :|bCRC Press,|c2016
300 vi,204 p :|bill ;|c25 cm.
504 Includes bibliographical references and index.
505 0 Getting a drug into the body: absorption -- Getting a drug
to its site of action: distribution -- Inactivating drugs:
phase 1 drug metabolism -- Phase 2 drug metabolism and
methods of excretion -- The concept of a drug's half-life:
an estimate of the rate of elimination of different drugs-
- Receptor function and intercellular signalling -- The
central role of receptors in drug action -- Drugs that
block enzymes: understanding NSAID therapy in inflammation
-- The principal targets for drug action -- Calcium ion
for the prescriber -- Introduction to drugs in the central
nervous system -- CNS drugs whose action is (a) understood,
(b) unknown/speculative -- The actions of CNS drugs used
to treat anxiety, insomnia and life-threatening status
epilepticus -- Drugs used to treat Parkinsonism -- Pain
and analgesics -- How anti-emetic drugs work --
Antipsychotic drugs -- Antidepressant drugs -- Anti-
epileptic drugs -- Drugs of abuse: hallucinogens and CNS
stimulants -- Alzheimer's disease -- How the many
antidiabetic drugs work -- Treating severe chronic
inflammation --The scientific basis of prescribing forthe
elderly --Antibacterial action and bacterial resistance --
How to prevent adverse drug interactions - ADIs -- How to
predict and avoid adverse drug reactions to single drugs -
ADRs -- Why consider practice formulary? --Getting new
drugs to market: licensing medicines for human use -- The
problem of patients' n-compliance with their medication -
'non-concordance'.
520 A concise textbook providing a clear description of drug
absorption, distribution, action, metabolism and adverse
effects, this title provides the information needed in a
straightforward way to ensure informed, safe and cost-
effective prescribing
650 0 Pharmacology
650 0 Drugs|xPrescribing
650 2 Pharmacology