| Edition |
7th ed. |
| Description |
xvii, 910 p : ill (some color) ; 24 cm. |
| Bibliography |
Includes bibliographical references and index. |
| Contents |
Introduction to biopharmaceutics and pharmacokinetics -- Mathematic fundamentals in pharmacokinetics -- Biostatistics -- One compartment open model : IV bolus injection -- Multicompartmental models : IV bolus injection -- Intravenous infusion -- Drug elimination and clearance -- Pharmacokinetics of oral absorption -- Multiple dosage regimens -- Nonlinear pharmacokinetics -- Physiologic drug distribution and protein binding -- Renal and hepatic elimination of drugs -- Pharmacogenetics and drug metabolism -- Physiologic factors related to drug absorption -- Biopharmaceutic considerations in drug product design -- Drug product performance, in vivo : bioavailability and bioequivalence -- Biopharmaceutic aspects of the active pharmaceutical ingredient and pharmaceutical equivalence -- Impact of biopharmaceutics on drug product quality and clinical efficacy -- Modified release drug products and drug devices -- Targeted drug delivery systems and biotechnology products -- Relationship between pharmacokinetic and pharmacodynamics -- Application of pharmacokinetics in clinical situations -- Application of pharmacokinetics in specific populations -- Dosage adjustment in renal and hepatic disease -- Empirical models, mechanistic models, statistical moment and noncompartmental analysis. |
| Subject |
Biopharmaceutics
|
|
Pharmacokinetics
|
| Added Author |
Shargel, Leon, 1941- , editor
|
|
Yu, Andrew B. C., 1945-, editor
|
| Added Title |
Applied biopharmaceutics and pharmacokinetics. |
| Cover Title |
Shargel & Yu's Applied biopharmaceutics and pharmacokinetics. |
| ISBN |
9789814670241 |
|
9780071830935 (hardcover : alk. paper) |
|
0071830936 (hardcover : alk. paper) |
|
9814670243 (pbk.) |
|
